[Frequent return as a novel strategy for tuberculosis treatment adherence].
نویسندگان
چکیده
OBJECTIVE Treatment dropout is one of the major obstacles to the control of tuberculosis. The aim of the present study was to evaluate the frequent return strategy instituted at the Tuberculosis Control Program, as well as the program as a whole, identifying and quantifying potential risk factors for dropout. METHODS The present study was conducted in Ubatuba, Southeastern Brazil. All patients (n=244) notified by the Tuberculosis Control Program in the two years preceding and the two years following the introduction of the frequent return strategy in 1999 were included. We carried out a descriptive analysis of the data and analyzed treatment results and program evaluation indicators. We performed univariate and multivariate analysis in order to identify potential risk factors associated with dropout. We also analyzed the frequent return strategy using chi-squared tests. RESULTS The strategy reduced the risk of treatment dropout from 12.3% to 4.9%. Risk factors associated with dropout were lack of schooling (OR=3.01; p=0.051), unemployment (OR=3.36; p=0.046), and alcohol dependence (OR=3.56; p=0.014). CONCLUSIONS The frequent return strategy reduced the risk of treatment dropout, although results did not reach statistical significance due to the small number of dropouts. This strategy may be an alternative for the supervised treatment for all patients recommended by the World Health Organization.
منابع مشابه
Identification of Mycobacterium tuberculosis adherence-mediating components: a review of key methods to confirm adhesin function
Anti-adhesion therapy represents a potentially promising avenue for the treatment and prevention of tuberculosis in a post-antibiotic era. Adhesins are surface-exposed microbial structures or molecules that enable pathogenic organisms to adhere to host surfaces, a fundamental step towards host infection. Although several Mycobacterium tuberculosis adhesins have been identified, it is predicted ...
متن کاملFostering Directly Observed Treatment in Tuberculosis: A Program Manager’s Perspective
Global Tuberculosis (TB) report (2013) has revealed that an estimated 8.6 million people developed TB of which, India accounts for almost 26% of the cases. These estimates clearly suggest that the country’s efforts to achieve Millennium Development Goal 6 by 2015 have not delivered the desired output. In India, the TB prevention and control activities are supervised and implemented under the Re...
متن کاملAssessment of Adherence to Anti-Tuberculosis Treatment among Patients with Tuberculosis in Qom Province in 2019 (Iran)
Background and Objectives: Despite the implementation of effective preventive and therapeutic programs, the expected success in reducing and controlling tuberculosis (TB) cases, has not yet been achieved. The purpose of the current study was to evaluate adherence to anti-TB drug regimen and its related factors in patients with TB in Qom province. Methods: This descriptive cross-sectional study,...
متن کاملRegular Reminding of the Potential Serious Complications of Poor Adherence to Treatment: A Strategy for Improving Treatment Adherence in Beta-Thalassemia Major Patients
Globally, β-Thalassemia Major (β-TM) is the most commonly inherited hemolytic anemia, with a high incidence rate in Southeast Asia, the Middle East and Mediterranean countries. Patients with β-TM require lifelong adherence to their distressing treatment regimens, including regular blood transfusions and daily chelation therapy.
متن کاملThe Mediating Role of Coping Strategies in the Relationship between Self-compassion and Adherence to Treatment in Cardiovascular Patients
Background & aim: Treatment adherence is one of the main factors in achieving maximum clinical efficacy. It seems that self-compassion and coping strategies of patients, can be effective on improving treatment adherence. The aim of this study was to investigate the mediating role of coping strategies in the relationship between self-compassion with treatment adherence in cardiovascular patients...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Revista de saude publica
دوره 39 6 شماره
صفحات -
تاریخ انتشار 2005